Denise (Dennis) Bryson, played by David Duchovny, is a cross-dressing DEA agent who investigates drug allegations against Dale Cooper. The character’s binary identity reflects the dualistic leitmotif of the series. It is unclear from the series whether Bryson would self-identify as a cross-dresser, a transvestite or transgender. Bryson began wearing women's clothing during an undercover operation and found that it relaxed him. Bryson identifies himself as "Denise," wears women's clothing and presents female behavior during working hours and otherwise. When required for a sting operation, Bryson dons a man's suit and goes by "Dennis." Bryson comes to Twin Peaks when Cooper is accused by the Mounties and the FBI of misfeasance for his handling of the rescue of Audrey Horne from One-Eyed Jack's and the alleged theft of cocaine from an RCMP stakeout. Cooper quickly determines that the "Mountie" accusing him is himself involved in drug dealing with Jacques Renault and Hank Jennings. This leads to the stakeout at Dead Dog Farm, in which Bryson's "feminine side" allows her to effect the rescue of Agent Cooper.
David Duchovny would later go on to play another more famous agent: Special Agent Fox Mulder of the FBI in The X-Files.